refine, point mutations


The parameter can have the values yes or no.


  1. No error message is generated when an uninterpretable value is entered for this parameter.
  2. If no value is set, the default value is no.


The last step in the refinement process is to test the selected sequences for the possibility of a point mutation in each one of the peptides generated with the initial cleavage chemistry. When this parameter is set to yes, point mutations are checked. Otherwise, this step is skipped.

See the explanation of point mutation analysis supplied with the main X! TANDEM documentation, using the link given below.

see also: refine | X! TANDEM point mutations

X! TANDEM API description project